HTLV-I associated myelopathy/tropical spastic paraparesis. Report of the first cases in Rio Grande do Sul, Brazil.
نویسندگان
چکیده
During the 80's, the HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) was identified in regions such as the Caribe, South Africa, Southern India, Seychelles Islands, Ivory Coast and Southern Japan. Those areas were found to be endemic for the HTLV-I, the etiologic agent for HAM/TSP. Towards the end of that decade and at the beginning of the 90's, several authors have described cases in non-tropical areas or in areas not known to be endemic for the disease as the United States and Europe. Papers published regarding the cases in Brazil have described its presence in the North, Northeastern and Southeastern areas.
منابع مشابه
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Human T lymphotropic virus type I (HTLV-I) is a retrovirus which is associated with adult T cells leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a minority of HTLV-I-infected individuals. It is not clear why a minority of HTLV-I-infected individuals develop HAM/TSP and majority remains lifelong carriers. It seems that the interaction between the v...
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To investigate candidate genes that influence the risk of HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), we analyzed 6 single nucleotide polymorphisms (SNP) in the interleukin-10 (IL-10) promoter region. METHODS: 280 cases of HAM/TSP patients and 255 HTLV-I seropositive asymptomatic carriers (HCs) from Kagoshima, Japan were studied. All subjects gave written informed conse...
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Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Only a limited percentage of infected individuals develop disease in response to the virus while the majority remain asymptomatic and HAM/TSP is the most common clinical manifestation of the virus. HAM/TSP is an inflamma...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 53 3-B شماره
صفحات -
تاریخ انتشار 1995